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Software for ECG analysis
Plch, Vít ; Hejč, Jakub (referee) ; Ronzhina, Marina (advisor)
This bachelor thesis deals with design and construction of tool for analysing electrocardiograms. The theoretical part deals with the origin of the action potential, propagation of the action potential through conduction system of the heart, failure of electrical impulse propagation through the con-duction system; different aspects of disorders, which can be found in experimental electrograms recorded from animal isolated hearts (database of electrograms, the Department of Biomedical En-gineering, FEEC, BUT), are also discussed. Software for electrograms draw and annotation available on the DBME, namely EG_Anotation and EG_RR_View, are described. As a result, the design and construct of ECG_ANN, the tool for the electrograms annotation, is proposed with regard to the advantages and disadvantages of mentioned software. At the end of the bachelor thesis there are the guide for ECG_ANN and discussion about problems which appears in design and construct of this tool.
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Electrogram processing and analysis
Hanák, Pavel ; Kolářová, Jana (referee) ; Janoušek, Oto (advisor)
The aim of the study was focused on problem of electrograms recording from alive tissue. Study of electrograms recording was extended with noise analysis and its elimination. Elimination of noise and disturption was made in program Matlab; lowpass filtration and wavelet transformation was used. Application for electrograms analysis was developed in latter part of this work.
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Biofeedback and its practical use
Dvořák, Jiří ; Hrozek, Jan (referee) ; Čmiel, Vratislav (advisor)
The aim of this work is describe common methods of biological feedback therapy that is used to treat some psychosomatic diseases. Subsequently, the description is focused on minimal brain dysfunction treatment by the help of EEG biofeedback. Properties and technical requirements for this therapy are concretized. The last part of this thesis is dedicated to the design and realization of practical software tool for EEG biofeedback therapy which is made in LabView 7.1. The M535 acquisition unit and NI USB-6221 measuring device are used for hardware solution.
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Measurement of Isolated Cardiac Muscle Cell Lenght in real time
Klabal, Petr ; Sekora, Jiří (referee) ; Chmelař, Milan (advisor)
Diploma thesis deals with the basic description of cardiac muscle cells, the mechanism of its contraction and events associated with contractions. There are different types of methods which can be used for measuring of contractions and for evaluation of cell length. This work describe these methods and evaluate their pros and cons. Based on available information and technical possibilities is one of the methods chosen and used for the design of block diagram system for measuring of contraction of isolated heart cells in real time. The practical part of this diploma thesis deals with the designing of a system which allows processing the image of isolated cardiac muscle cells that facilitate the detection of the cells edge. For this purpose it was created a device that allows the user to select a single row from television signal containing the image information from a location where is the currently selected row. Thus obtained image information can be used for cells edge detection and measuring of its length and contractions.
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Optical Measurement of Electromechanical Characteristics of Heart Cells
Čmiel, Vratislav ; Križanová,, Olga (referee) ; Babula, Petr (referee) ; Provazník, Ivo (advisor)
Dissertation is focused on the application of optical measurement methods using techniques of optical microscopy and fluorescence microscopy in measurements of electromechanical characteristics of isolated cardiac cells and clusters of differentiated cardiomyocytes. The first proposed method uses a practical combination of fluorescence microscopy equipped with fluorescent fast and high-resolution camera and atomic force microscopy for simultaneous measurement of calcium transients and contraction of cardiomyocyte clusters. The signals obtained undergoes filtration, processing and analysis. Result function parameters obtained by analyzing signals after application of caffeine are evaluated by comparison with functional parameters obtained during the control measurement. The second proposed method is applied to the cardiomyocyte clusters for the purpose of cardiomyocyte contraction signals measurement. The signals obtained by optical methods are analyzed and compared with the reference signal obtained using atomic force microscopy. Optical measurement method of cell contractins based on detection of cell ends using adjusting of microscopy images by re-sharpening and fluorescence method for cardiomyocyte contractions measurements were designed to increase realiability in simultaneous measurement of cell contractions simultaneously with calcium transients in isolated cardiomyocytes experiments.
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Transportable ECG monitor
Vepřková, Hana ; Rozman, Jiří (referee) ; Chmelař, Milan (advisor)
The first two chapters are devoted to theoretical analysis of issues relating to portable EKG monitor. This chapters are aimed to further acquaint the reader with the issue for subsequent easier of understanding on further steps in the implementation of the device which will be contain in the following chapters. The first chapter is mainly a medical nature. We describe the anatomy and functional properties of the heart. In the next chapter we are deal with detail of electrocardiograph and the conditions for its proper function. Other chapters are devoted to the actual implementation of the facility. We are dealing with the issue of build functional portable EKG monitor. This practical part begins by fourth chapter, which consists block diagram of the device and discusses the required parameters. Next most extensive chapter is devoted to a detailed breakdown of the electrical circuit, including the calculation of the individual components. The last chapter describes the implementation and outcome measurements on test persons.
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Optical Method to Evaluate the Contractile Function of Isolated Cardiac Myocytes
Kopečný, Josef ; Harabiš, Vratislav (referee) ; Čmiel, Vratislav (advisor)
In this master´s thesis we will firstly focused on the description of a cyte in terms of structure as well as in terms of electrical and chemical processes. We will examine a processes, which make a contraction and the processes on cyte membrane. We will also analyse image processing methods and methods for measuring the contraction. The block diagram will be designed and requirements for the measuring platform will be specified. The programme will be realized in LabWIEV programming language.
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Electronics for muscle activity monitoring
Lavička, Jiří ; Vlach, Radek (referee) ; Krejčí, Petr (advisor)
This thesis describes the design and compilation of device for monitoring of muscle activity. You can find there a generally introduction of monitoring of this activity. Futheremore it pushes ahead process of plan of electronics and DPS. In final part of this thesis is shown summary of whole device and also there is a example of measurement.
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Device for measuring the electrical activity of muscles
Slouka, Petr ; Chmelař, Milan (referee) ; Balogh, Jaroslav (advisor)
This thesis contains introduction to the basic principles of creation and transmission of action potentials. Afterwards it is outlined development of electromyography which is used for measuring electrical signals from muscles and attributes of electromyographic signal. Next part describes design of the device for measuring electrical activity of muscles. Thesis contains diagrams of the integrated circuit, design of printed circuit board and list of components which are needed for realization of the device.
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Optical detection of electrograms
Hanák, Pavel ; Kozumplík, Jiří (referee) ; Chmelař, Milan (advisor)
The aim of the study was focused on problem of electrograms recording with using voltage sensitive dyes. Study of electrograms recording was extended with thema of optical detectors suitable for measurement and noise analysis. Elimination of noise and disturption was made in program Matlab; lowpass filtration and wavelet transformation was used. Application for electrograms analysis was developed in latter part of this work.
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